Publications
Currently more than 90 publications, in collaboration with more than 200 co-authors; over 70% are a result of international collaboration projects. Over 80% have been published in top-quartile international journals, and over 50% are within the top-quartile most cited documents worldwide.
Profiles
An updated list can be found in several places:
• ORCID
• Scopus
Other sites containing publications and other info:
• OpenAlex
• Loop
Searchable list
Below is a complete list (the box can be used for a more advanced search):
| Number | Reference | URL |
|---|---|---|
97 |
Liu X., Jimenez-Alesanco A., Li Z., Rizzuti B., Neira J.L., Estaras M., Peng L., Chuluyan E., Garona J., Gottardo F., Velazquez-Campoy A., Xia Y., Abian O., Santofimia-Castaño P., Iovanna J. Development of an efficient NUPR1 inhibitor with anticancer activity Scientific Reports, 14: 29515–1-20, 2024 | DOI |
96 |
Sancineto L., Mangiavacchi F., Dabrowska A., Pacuła-Miszewska A.J., Obieziurska-Fabisiak M., Scimmi C., Ceccucci V., Kong J., Zhao Y., Ciancaleoni G., Nascimento V., Rizzuti B., Bortoli M., Orian L., Kula-Pacurar A., Yang H., Ścianowski J., Lei Y., Pyrc K., Santi C. New insights in the mechanism of the SARS-CoV-2 Mpro inhibition by benzisoselenazolones and diselenides Scientific Reports, 14: 24751–1-17, 2024 (preprint available on ChemRxiv, 2024) | DOI (1) DOI (2) |
95 |
Neira J.L., Rizzuti B., Abian O., Velazquez-Campoy A. Isolated auto-citrullinated regions of PADI4 associate to the intact protein without altering their disordered conformation Biophysical Chemistry, 312: 107288–1-12, 2024 (erratum available on Biophysical Chemistry, 313: 107295–1-1, 2024) | DOI (1) DOI (2) |
94 |
Talia M., Cirillo F., Scordamaglia D., Di Dio M., Zicarelli A., De Rosis S., Miglietta A.M., Capalbo C., De Francesco E.M., Belfiore A., Grande F., Rizzuti B., Occhiuzzi M.A., Fortino G., Guzzo A., Greco G., Maggiolini M., Lappano R. The G Protein Estrogen Receptor (GPER) is involved in the resistance to the CDK4/6 inhibitor palbociclib in breast cancer Journal of Experimental & Clinical Cancer Research, 43: 171–1-22, 2024 | DOI |
93 |
Araujo-Abad S., Rizzuti B., Soto-Conde L., Vidal M., Abian O., Velazquez-Campoy A., Neira J.L., de Juan Romero C. Citrullinating enzyme PADI4 and transcriptional repressor RING1B bind in cancer cells International Journal of Biological Macromolecules, 274: 133163–1-14, 2024 | DOI |
92 |
Cirillo F., Spinelli A., Talia M., Scordamaglia D., Santolla M.F., Grande F., Rizzuti B., Maggiolini M., Gérard C., Lappano R. Estetrol/GPER/SERPINB2 transduction signaling inhibits the motility of triple-negative breast cancer cells Journal of Translational Medicine, 22: 450–1-15, 2024 | DOI |
91 |
Araujo-Abad S., Rizzuti B., Vidal M., Abian O., Fárez-Vidal M.E., Velazquez-Campoy A., de Juan Romero C., Neira J.L. Unveiling the binding between the armadillo-repeat domain of Plakophilin 1 and the intrinsically disordered transcriptional repressor RYBP Biomolecules, 14: 561–1-17, 2024 | DOI |
90 |
Torcasio R., Gallo Cantafio M.E., Veneziano C., De Marco C., Ganino L., Valentino I., Occhiuzzi M.A., Perrotta I.D., Mancuso T., Conforti F., Rizzuti B., Martino E.A., Gentile M., Neri A., Viglietto G., Grande F., Amodio N. Targeting of mitochondrial fission through natural flavanones elicits anti-myeloma activity Journal of Translational Medicine, 22: 208–1-17, 2024 | DOI |
89 |
Occhiuzzi M.A., Ioele G., De Luca M., Rizzuti B., Scordamaglia D., Lappano R., Maggiolini M., Garofalo A., Grande F. Dissecting CYP1A2 activation by arylalkanoic acid prodrugs toward the development of anti-inflammatory agents International Journal of Molecular Sciences, 25: 435–1-15, 2024 | DOI |
88 |
Rizzuti B., Abian O., Velazquez-Campoy A., Neira J.L. Conformational stability of the N-terminal region of MDM2 Molecules, 28: 7578–1-21, 2023 | DOI |
87 |
Araujo-Abad S., Rizzuti B., Villamarin-Ortiz A., Pantoja-Uceda D., Moreno-Gonzalez C.M., Abian O., Velazquez-Campoy A., Neira J.L., de Juan Romero C. New insights into cancer: MDM2 binds to the citrullinating enzyme PADI4 Protein Science, 32: e4723–1-21, 2023 | DOI |
86 |
Araujo-Abad S., Fuentes-Baile M., Rizzuti B., Bazán J.F., Villamarin-Ortiz A., Saceda M., Fernández E., Vidal M., Abian O., Velazquez-Campoy A., de Juan Romero C., Neira J.L. The intrinsically disordered, epigenetic factor RYBP binds to the citrullinating enzyme PADI4 in cancer cells International Journal of Biological Macromolecules, 246: 125632–1-14, 2023 | DOI |
85 |
Araujo-Abad S., Neira J.L., Rizzuti B., García-Morales P., de Juan Romero C., Santofimia-Castaño P., Iovanna J. Intrinsically disordered chromatin protein NUPR1 binds to the enzyme PADI4 Journal of Molecular Biology, 435: 168033–1-18, 2023 | DOI |
84 |
Guglielmelli A., Bartucci R., Rizzuti B., Palermo G., Guzzi R., Strangi G. The interaction of tryptophan enantiomers with model membranes is modulated by polar head type and physical state of phospholipids Colloids and Surfaces B: Biointerfaces, 224: 113216–1-10, 2023 | DOI |
83 |
Kampa M., Lappano R., Grande F., Rizzuti B., Maggiolini M., Castanas E., Jacquot Y. Promising perspectives of the antiproliferative GPER inverse agonist ERα17p in breast cancer Cells, 12: 653–1-12, 2023 | DOI |
82 |
Da Silva Gomes L.S., Neto J.S.S., di Leo I., Barbosa C.G., Moraes C.B., Freitas L.H., Rizzuti B., Santi C., Nascimento V. Ecofriendly aminochalcogenation of alkenes: a green alternative to obtain compounds with potential anti-SARS-CoV-2 activity New Journal of Chemistry, 47: 6591-6601, 2023 | DOI |
81 |
Neira J.L., Rizzuti B., Araujo-Abad S., Abian O., Fárez-Vidal M.E., Velazquez-Campoy A., de Juan Romero C. The armadillo-repeat domain of Plakophilin 1 binds to human enzyme PADI4 Biochimica et Biophysica Acta - Proteins and Proteomics, 1871: 140868–1-10, 2023 | DOI |
80 |
Rizzuti B., Iovanna, J.L., Neira J.L. Deciphering the binding of the nuclear localization sequence of Myc protein to the nuclear carrier Importin α3 International Journal of Molecular Sciences, 23: 15333–1-19, 2022 | DOI |
79 |
Rizzuti B. Nanomedicines meet disordered proteins: A shift from traditional materials and concepts to innovative polymers Journal of Personalized Medicine, 12: 1662–1-4, 2022 | DOI |
78 |
Neira J.L., Rizzuti B., Abián O., Araujo-Abad S., Velázquez-Campoy A., de Juan Romero C. Human enzyme PADI4 binds to the nuclear carrier Importin α3 Cells, 11: 2166–1-28, 2022 | DOI |
77 |
De Luca M., Occhiuzzi M.A., Rizzuti B., Ioele G., Ragno G., Garofalo A., Grande F. Interaction of letrozole and its degradation products with aromatase: chemometric assessment of kinetics and structure-based binding validation Journal of Enzyme Inhibition and Medicinal Chemistry, 37: 1600-1609, 2022 | DOI |
76 |
Neira J.L., Araujo-Abad S., Cámara-Artigas A., Rizzuti B., Abian O., Giudici A.M., Velazquez-Campoy A., de Juan Romero C. Biochemical and biophysical characterization of PADI4 supports its involvement in cancer Archives of Biochemistry and Biophysics, 717: 109125–1-16, 2022 | DOI |
75 |
Rizzuti B. Molecular simulations of proteins: From simplified physical interactions to complex biological phenomena Biochimica et Biophysica Acta - Proteins and Proteomics, 1870: 140757–1-13, 2022 | DOI |
74 |
Pacheco-Garcia J.L., Loginov D., Rizzuti B., Vankova P., Neira J.L., Kavan D., Mesa-Torres N., Guzzi R., Man P., Pey A.L. A single evolutionarily divergent mutation determines the different FAD-binding affinities of human and rat NQO1 due to site-specific phosphorylation FEBS Letters, 596: 29–41, 2022 | DOI |
73 |
Neira J.L., Ortega-Alarcón D., Rizzuti B., Palomino-Schätzlein M., Velázquez-Campoy A., Falcó A. Residual helicity at the active site of the histidine phosphocarrier, HPr, modulates binding affinity to its natural partners International Journal of Molecular Sciences, 22: 10805–1-18, 2021 | DOI |
72 |
Rizzuti B., Lan W., Santofimia-Castaño P., Zhou Z., Velázquez-Campoy A., Abián O., Peng L., Neira J.L., Xia Y., Iovanna J.L. Design of inhibitors of the intrinsically disordered protein NUPR1: balance between drug affinity and target function Biomolecules, 11: 1453–1-19, 2021 | DOI |
71 |
Grande F., Occhiuzzi M.A., Perri M.R., Ioele G., Rizzuti B., Statti G., Garofalo A. Polyphenols from citrus Tacle® extract endowed with HMGCR inhibitory activity: an antihypercholesterolemia natural remedy Molecules, 26: 5718–1-11, 2021 | DOI |
70 |
Rizzuti B., Ceballos-Laita L., Ortega-Alarcon D., Jimenez-Alesanco A., Vega S., Grande F., Conforti F., Abian O., Velazquez-Campoy A. Sub-micromolar inhibition of SARS-CoV-2 3CLpro by natural compounds Pharmaceuticals, 14: 892–1-10, 2021 | DOI |
69 |
Bonucci A., Palomino-Schätzlein M., Malo de Molina P., Arbe A., Pierattelli R., Rizzuti B., Iovanna J.L., Neira J.L. Crowding effects on the structure and dynamics of the intrinsically disordered nuclear chromatin protein NUPR1 Frontiers in Molecular Biosciences, 8: 684622–1-14, 2021 | DOI |
68 |
Mangiavacchi F., Botwina P., Menichetti E., Bagnoli L., Rosati O., Marini F., Fonseca S.F., Abenante L., Alves D., Dabrowska A., Kula-Pacurar A., Ortega-Alarcon D., Jimenez-Alesanco A., Ceballos-Laita L., Vega S., Rizzuti B., Abian O., Lenardão E.J., Velazquez-Campoy A., Pyrc K., Sancineto L., Santi C. Seleno-functionalization of quercetin improves the non-covalent inhibition of Mpro and its antiviral activity in cells against SARS-CoV-2 International Journal of Molecular Sciences, 22: 7048–1-20, 2021 | DOI |
67 |
Grande F., Giordano F., Occhiuzzi M.A., Rocca C., Ioele G., De Luca M., Ragno G., Panno M.L., Rizzuti B., Garofalo A. Toward multitasking pharmacological COX-targeting agents: non-steroidal anti-inflammatory prodrugs with antiproliferative effects Molecules, 26: 3940–1-18, 2021 | DOI |
66 |
Neira J.L., Jiménez-Alesanco A., Rizzuti B., Velazquez-Campoy A. The nuclear localization sequence of the epigenetic factor RYBP binds to human importin α3 Biochimica et Biophysica Acta - Proteins and Proteomics, 1869: 140670–1-13, 2021 | DOI |
65 |
Neira J.L., Rizzuti B., Ortega-Alarcón D., Giudici A.M., Abián O., Fárez-Vidal M.E., Velázquez-Campoy A. The armadillo-repeat domain of plakophilin 1 binds the C-terminal sterile alpha motif (SAM) of p73 Biochimica et Biophysica Acta - General Subjects, 1865: 129914–1-12, 2021 | DOI |
64 |
Annesi F., Hermoso-Durán S., Rizzuti B., Bruno R., Pirritano D., Petrone A., Del Giudice F., Ojeda J., Vega S., Sanchez-Gracia O., Velazquez-Campoy A., Abian O., Guzzi R. Thermal liquid biopsy (TLB) of blood plasma as a potential tool to help in the early diagnosis of multiple sclerosis Journal of Personalized Medicine, 11: 295–1-16, 2021 | DOI |
63 |
Rizzuti B., Grande F., Conforti F., Jimenez-Alesanco A., Ceballos-Laita L., Ortega-Alarcon D., Vega S., Reyburn H.T., Abian O., Velazquez-Campoy A. Rutin is a low micromolar inhibitor of SARS-CoV-2 main protease 3CLpro: Implications for drug design of quercetin analogs Biomedicines, 9: 375–1-20, 2021 | DOI |
62 |
Rocca C., De Bartolo A., Grande F., Rizzuti B., Pasqua T., Giordano F., Granieri M.C., Occhiuzzi M.A., Garofalo A., Amodio N., Cerra M.C., Schneider F., Panno M.L., Metz-Boutigue M.H., Angelone T. Cateslytin abrogates lipopolysaccharide-induced cardiomyocyte injury by reducing inflammation and oxidative stress through toll like receptor 4 interaction International Immunopharmacology, 94: 107487–1-12, 2021 | DOI |
61 |
Santofimia-Castaño P., Rizzuti B., Pey A.L., Fárez-Vidal M.E., Iovanna J.L., Neira J.L. Intrinsically disordered protein NUPR1 binds to the armadillo-repeat domain of Plakophilin 1 International Journal of Biological Macromolecules, 170: 549-560, 2021 | DOI |
60 |
Hornos F., Feng H.-Z., Rizzuti B., Palomino-Schätzlein M., Wieczorek D., Neira J.L., Jin J.-P. The muscle-relaxing C-terminal peptide from troponin I populates a nascent helix, facilitating binding to tropomyosin with a potent therapeutic effect Journal of Biological Chemistry, 296: 100228–1-18, 2021 | DOI |
59 |
Rocca C., Grande F., Granieri M.C., Colombo B., De Bartolo A., Giordano F., Rago V., Amodio N., Tota B., Cerra M.C., Rizzuti B., Corti A., Angelone T., Pasqua T. The chromogranin A1-373 fragment reveals how a single change in the protein sequence exerts strong cardioregulatory effects by engaging neuropilin-1 Acta Physiologica, 231: e13570–1-21, 2021 | DOI |
58 |
Neira J.L., Rizzuti B., Jiménez-Alesanco A., Abián O., Velázquez-Campoy A., Iovanna J.L. The paralogue of the intrinsically disordered nuclear protein 1 has a nuclear localization sequence that binds to human importin α3 International Journal of Molecular Sciences, 21: 7428–1-19, 2020 | DOI |
57 |
Aloi E., Rizzuti B., Guzzi R., Bartucci R. Binding of warfarin differently affects the thermal behaviour and chain packing of anionic, zwitterionic and cationic lipid membranes Archives of Biochemistry and Biophysics, 694: 108599–1-10, 2020 | DOI |
56 |
Neira J.L., Rizzuti B., Jiménez-Alesanco A., Palomino-Schätzlein M., Abián O., Velázquez-Campoy A., Iovanna J.L. A phosphorylation-induced switch in the nuclear localization sequence of the intrinsically disordered protein NUPR1 hampers binding to importin Biomolecules, 10: 1313–1-22, 2020 | DOI |
55 |
Lan W., Santofimia-Castaño P., Swayden M., Xia Y., Zhou Z., Audebert S., Camoin L., Huang C., Peng L., Jiménez-Alesanco A., Velázquez-Campoy A., Abian O., Lomberk G., Urrutia R., Rizzuti B., Geli V., Soubeyran P., Neira J.L., Iovanna J.L. ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents JCI Insight, 5: e138117–1-19, 2020 | DOI |
54 |
Abian O., Ortega-Alarcon D., Jimenez-Alesanco A., Ceballos-Laita L., Vega S., Reyburn H.T., Rizzuti B., Velazquez-Campoy A. Structural stability of SARS-CoV-2 3CLpro and identification of quercetin as an inhibitor by experimental screening International Journal of Biological Macromolecules, 164: 1693-1703, 2020 | DOI |
53 |
Grande F., Occhiuzzi M.A., Lappano R., Cirillo F., Guzzi R., Garofalo A., Jacquot Y., Maggiolini M., Rizzuti B. Computational approaches for the discovery of GPER targeting compounds Frontiers in Endocrinology, 11: 517–1-8, 2020 | DOI |
52 |
Díaz-García C., Hornos F., Giudici A.M., Cámara-Artigas A., Luque-Ortega J.R., Arbe A., Rizzuti B., Alfonso C., Forwood J.K., Iovanna J.L., Gómez J., Prieto M., Coutinho A., Neira J.L. Human importin α3 and its N-terminal truncated form, without the importin-β-binding domain, are oligomeric species with a low conformational stability in solution Biochimica et Biophysica Acta - General Subjects, 1864: 129609–1-14, 2020 | DOI |
51 |
Neira J.L., Ortore M.G., Florencio F.J., Muro-Pastor M.I., Rizzuti B. Dynamics of the intrinsically disordered inhibitor IF7 of glutamine synthetase in isolation and in complex with its partner Archives of Biochemistry and Biophysics, 683: 108303–1-11, 2020 | DOI |
50 |
Rizzuti B., Grande F. Virtual screening in drug discovery: a precious tool for a still-demanding challenge Book chapter, chapter 14: 309-327, 2020 in: "Protein Homeostasis Diseases – Mechanisms and Novel Therapies", Academic Press (Elsevier), pp. 1-420 | DOI (1) DOI (2) |
49 |
Ricciardi L., Guzzi R., Rizzuti B., Ionescu A., Aiello I., Ghedini M., La Deda M. Anionic versus neutral Pt(II) complexes: the relevance of the charge for human serum albumin binding Journal of Inorganic Biochemistry, 206: 111024–1-9, 2020 | DOI |
48 |
Rizzuti B., Bartucci R., Guzzi R. Effects of polar head nature and tail length of single-chain lipids on the conformational stability of β-lactoglobulin Journal of Physical Chemistry B, 124: 944-952, 2020 | DOI |
47 |
Santofimia-Castaño P., Rizzuti B., Xia Y., Abián O.,Peng L., Velázquez-Campoy A., Neira J.L., Iovanna J. Targeting intrinsically disordered proteins involved in cancer Cellular and Molecular Life Sciences, 77: 1695-1707, 2020 | DOI |
46 |
Santofimia-Castaño P., Xia Y., Peng L., Velázquez-Campoy A., Abián O., Lan W., Lomberk G., Urrutia R., Rizzuti B., Soubeyran P., Neira J.L., Iovanna J. Targeting the stress-induced protein NUPR1 to treat pancreatic adenocarcinoma Cells, 8: 1453–1-9, 2019 | DOI |
45 |
Rizzuti B., Bartucci R., Pey A.L., Guzzi R. Warfarin increases thermal resistance of albumin through stabilization of the protein lobe that includes its binding site Archives of Biochemistry and Biophysics, 676: 108123–1-8, 2019 | DOI |
44 |
Ceramella J., Caruso A., Occhiuzzi M.A., Iacopetta D., Barbarossa A., Rizzuti B., Dallemagne P., Rault S., El-Kashef H., Saturnino C., Grande F., Sinicropi M.S. Benzothienoquinazolinones as new multi-target scaffolds: Dual inhibition of human Topoisomerase I and tubulin polymerization European Journal of Medicinal Chemistry, 181: 111583–1-9, 2019 | DOI |
43 |
Cirillo F., Lappano R., Bruno L., Rizzuti B., Grande F., Guzzi R., Briguori S., Miglietta A.M., Nakajima M., Di Martino M.T., Maggiolini M. AHR and GPER mediate the stimulatory effects induced by 3-methylcholanthrene in breast cancer cells and cancer-associated fibroblasts (CAFs) Journal of Experimental & Clinical Cancer Research, 38: 335–1-18, 2019 | DOI |
42 |
Neira J.L., Palomino-Schätzlein M., Ricci C., Ortore M.G., Rizzuti B., Iovanna J.L. Dynamics of the intrinsically disordered protein NUPR1 in isolation and in its fuzzy complexes with DNA and prothymosin α Biochimica et Biophysica Acta - Proteins and Proteomics, 1867: 140252–1-13, 2019 | DOI |
41 |
Lappano R., Mallet C., Rizzuti B., Grande F., Galli G.R., Byrne C., Broutin I., Boudieu L., Eschalier A., Jacquot Y., Maggiolini M. The peptide ERα17p is a GPER inverse agonist that exerts antiproliferative effects in breast cancer cells Cells, 8: 590–1-19, 2019 | DOI |
40 |
Neira J.L., Correa J., Rizzuti B., Santofimia-Castaño P., Abián O., Velázquez-Campoy A., Fernández-Megía E., Iovanna J.L. Dendrimers as competitors of protein-protein interactions of the intrinsically disordered nuclear chromatin protein NUPR1 Biomacromolecules, 20: 2567-2576, 2019 | DOI |
39 |
Santofimia-Castaño P., Rizzuti B., Xia Y., Abián O., Peng L., Velázquez-Campoy A., Iovanna J., Neira J.L. Designing and repurposing drugs to target intrinsically disordered proteins for cancer treatment: using NUPR1 as a paradigm Molecular & Cellular Oncology, 6: e1612678–1-3, 2019 | DOI |
38 |
Santofimia-Castaño P., Xia Y., Lan W., Zhou Z., Huang C., Peng L., Soubeyran P., Velázquez-Campoy A., Abián O., Rizzuti B., Neira J.L., Iovanna J. Ligand-based design identifies a potent NUPR1 inhibitor exerting anticancer activity via necroptosis Journal of Clinical Investigation, 129: 2500-2513, 2019 | DOI |
37 |
Grande F., Occhiuzzi M.A., Rizzuti B., Ioele G., De Luca M., Tucci P., Svicher V., Aquaro S., Garofalo A. CCR5/CXCR4 dual antagonism for the improvement of HIV infection therapy Molecules, 24: 550–1-11, 2019 | DOI |
36 |
Pantoja-Uceda D., Neira J.L., Contreras L.M., Manton C.A., Welch D.R., Rizzuti B. The isolated C-terminal nuclear localization sequence of the breast cancer metastasis suppressor 1 is disordered Archives of Biochemistry and Biophysics, 664: 95-101, 2019 | DOI |
35 |
Casacchia T., Occhiuzzi M.A., Grande F., Rizzuti B., Granieri M.C., Rocca C., Gattuso A., Garofalo A., Angelone T., Statti G. A pilot study on the nutraceutical properties of the Citrus hybrid Tacle® as a dietary source of polyphenols for supplementation in metabolic disorders Journal of Functional Foods, 52: 370-381, 2019 | DOI |
34 |
Medina-Carmona E., Rizzuti B., Martín-Escolano R., Pacheco-García J.L., Mesa-Torres N., Neira J.L., Guzzi R., Pey A.L. Phosphorylation compromises FAD binding and intracellular stability of wild-type and cancer-associated NQO1: Insights into flavo-proteome stability International Journal of Biological Macromolecules, 125: 1275-1288, 2019 | DOI |
33 |
Neira J.L., Giudici A.M., Hornos F., Arbe A., Rizzuti B. The C terminus of the ribosomal-associated protein LrtA is an intrinsically disordered oligomer International Journal of Molecular Sciences, 19: 3902–1-16, 2018 | DOI |
32 |
Aloi E., Rizzuti B., Guzzi R., Bartucci R. Association of ibuprofen at the polar/apolar interface of lipid membranes Archives of Biochemistry and Biophysics, 654: 77-84, 2018 | DOI |
31 |
Contreras L.M., Sevilla P., Cámara-Artigas A., Hernández-Cifre J.G., Rizzuti B., Florencio F.J., Muro-Pastor M.I., de la Torre J.G., Neira J.L. The cyanobacterial ribosomal-associated protein LrtA from Synechocystis sp. PCC 6803 is an oligomeric protein in solution with chameleonic sequence properties International Journal of Molecular Sciences, 19: 1857–1-21, 2018 | DOI |
30 |
Neira J.L., Lopez M.B., Sevilla P., Rizzuti, B., Cámara-Artigas A., Vidal M., Iovanna J.L. The chromatin nuclear protein NUPR1L is intrinsically disordered and binds to the same proteins as its paralogue Biochemical Journal, 475: 2271-2291, 2018 | DOI |
29 |
Grande F., Rizzuti B., Occhiuzzi M.A., Ioele G., Casacchia T., Gelmini F., Guzzi R., Garofalo A., Statti G. Identification by molecular docking of homoisoflavones from Leopoldia comosa as ligands of estrogen receptors Molecules, 23: 894–1-14, 2018 | DOI |
28 |
Santofimia-Castaño P., Rizzuti B., Abián O., Velázquez-Campoy A., Iovanna J.L., Neira J.L. Amphipathic helical peptides hamper protein-protein interactions of the intrinsically disordered chromatin nuclear protein 1 (NUPR1) Biochimica et Biophysica Acta - General Subjects, 1862: 1283-1295, 2018 | DOI |
27 |
Guglielmelli A., Rizzuti B., Guzzi R. Stereoselective and domain-specific effects of ibuprofen on the thermal stability of human serum albumin European Journal of Pharmaceutical Sciences, 112: 122-131, 2018 | DOI |
26 |
Santofimia-Castaño P., Rizzuti B., Pey Á.L., Soubeyran P., Vidal M., Urrutia R., Iovanna J.L., Neira J.L. Intrinsically disordered chromatin protein NUPR1 binds to the C-terminal region of Polycomb RING1B Proceedings of the National Academy of Sciences of the USA, 114: E6332-E6341, 2017 | DOI |
25 |
José L. Neira, Jennifer Bintz, Maria Arruebo, Bruno Rizzuti, Thomas Bonacci, Sonia Vega, Angel Lanas, Adrian Velázquez-Campoy, Juan L. Iovanna, Olga Abian Blocking NUPR1 protein, a successful approach for pancreatic adenocarcinoma treatment Gastroenterology, 152: S42, 2017 | DOI |
24 |
Cozza C., Neira J.L., Florencio F.J., Muro-Pastor M.I., Rizzuti B. Intrinsically disordered inhibitor of glutamine synthetase is a functional protein with random-coil-like pKa values Protein Science, 26: 1105-1115, 2017 | DOI |
23 |
Neira J.L., Bintz J., Arruebo M., Rizzuti B., Bonacci T., Vega S., Lanas A., Velázquez-Campoy A., Iovanna J.L., Abián O. Identification of a drug targeting an intrinsically disordered protein involved in pancreatic adenocarcinoma Scientific Reports, 7: 39732–1-15, 2017 | DOI |
22 |
Evoli S., Mobley D.L., Guzzi R., Rizzuti B. Multiple binding modes of ibuprofen in human serum albumin identified by absolute binding free energy calculations Physical Chemistry Chemical Physics, 18: 32358-32368, 2016 (preprint available on bioRxiv, 2016) | DOI (1) DOI (2) |
21 |
Neira J.L., Martínez-Rodríguez S., Hernández-Cifre J.G., Cámara-Artigas A., Clemente P., Peralta S., Fernández-Moreno M.A., Garesse R., de la Torre J.G., Rizzuti B. Human COA3 is an oligomeric highly flexible protein in solution Biochemistry, 55: 6209-6220, 2016 | DOI |
20 |
Longo E., Ciuchi F., Guzzi R., Rizzuti B., Bartucci R. Resveratrol induces interdigitation in DPPC cell membrane model systems Colloids and Surfaces B: Biointerfaces, 148: 615–621, 2016 | DOI |
19 |
Stirpe A., Pantusa M., Rizzuti B., De Santo M.P., Sportelli L., Bartucci R., Guzzi R. Resveratrol induces thermal stabilization of human serum albumin and modulates the early aggregation stage International Journal of Biological Macromolecules, 92: 1049–1056, 2016 | DOI |
18 |
Neira J.L., Rizzuti B., Iovanna J.L. Determinants of the pKa values of ionizable residues in an intrinsically disordered protein Archives of Biochemistry and Biophysics, 598: 18-27, 2016 | DOI |
17 |
Rizzuti B., Bartucci R., Sportelli L., Guzzi R. Fatty acid binding into the highest affinity site of human serum albumin observed in molecular dynamics simulation Archives of Biochemistry and Biophysics, 579: 18-25, 2015 | DOI |
16 |
Guzzi R., Rizzuti B., Labate C., Zappone B., De Santo M.P. Ferric ions inhibit the amyloid fibrillation of β-lactoglobulin at high temperature Biomacromolecules, 16: 1794-1801, 2015 | DOI |
15 |
Evoli S., Guzzi R., Rizzuti B. Molecular simulations of β-lactoglobulin complexed with fatty acids reveal the structural basis of ligand affinity to internal and possible external binding sites Proteins: Structure, Function, and Bioinformatics, 82: 2609-2619, 2014 | DOI |
14 |
Pantusa M., Bartucci R., Rizzuti B. Stability of trans-resveratrol associated with transport proteins Journal of Agricultural and Food Chemistry, 62: 4384-4391, 2014 | DOI |
13 |
Evoli S., Guzzi R., Rizzuti B. Dynamics and unfolding pathway of chimeric azurin variants: insights from molecular dynamics simulation Journal of Biological Inorganic Chemistry, 18: 739-749, 2013 | DOI |
12 |
Rizzuti B., Daggett V. Using simulations to provide the framework for experimental protein folding studies Archives of Biochemistry and Biophysics, 531: 128–135, 2013 | DOI |
11 |
Zappone B., De Santo M.P., Labate C., Rizzuti B., Guzzi R. Catalytic activity of copper ions in the amyloid fibrillation of β-lactoglobulin Soft Matter, 9: 2412-2419, 2013 | DOI |
10 |
Guzzi R., Rizzuti B., Bartucci R. Dynamics and binding affinity of spin-labelled stearic acids in β-lactoglobulin: evidences from EPR spectroscopy and molecular dynamics simulation Journal of Physical Chemistry B, 116: 11608-11615, 2012 | DOI |
9 |
Stirpe A., Pantusa M., Rizzuti B., Sportelli L., Bartucci R., Guzzi R. Early stage aggregation of human serum albumin in the presence of metal ions International Journal of Biological Macromolecules, 49: 337-342, 2011 | DOI |
8 |
Rizzuti B., Pantusa M., Guzzi R. The role of Lys525 on the head-group anchoring of fatty acids in the highest affinity binding site of albumin Spectroscopy, 24: 159-163, 2010 | DOI |
7 |
Rizzuti B., Zappone B., De Santo M.P., Guzzi R. Native β-lactoglobulin self-assembles into a hexagonal columnar phase on a solid surface Langmuir, 26: 1090-1095, 2010 | DOI |
6 |
Rizzuti B., Sportelli L., Guzzi R. Molecular dynamics of amicyanin reveals a conserved dynamical core for blue copper proteins Proteins: Structure, Function, and Bioinformatics, 74: 961-971, 2009 | DOI |
5 |
Stirpe A., Rizzuti B., Pantusa M., Bartucci R., Sportelli L., Guzzi R. Thermally induced denaturation and aggregation of BLG-A: effect of Cu2+ and Zn2+ metal ions European Biophysics Journal with Biophysics Letters, 37: 1351-1360, 2008 | DOI |
4 |
Rizzuti B., Sportelli L., Guzzi R. Structural, dynamical and functional aspects of the inner motions in the blue copper protein azurin Biophysical Chemistry, 125: 532-539, 2007 | DOI |
3 |
Rizzuti B., Daggett V., Guzzi R., Sportelli L. The early steps in the unfolding of azurin Biochemistry, 43: 15604-15609, 2004 | DOI |
2 |
Rizzuti B., Swart M., Sportelli L., Guzzi R. Active site modeling in copper azurin molecular dynamics simulations Journal of Molecular Modeling, 10: 25-31, 2004 | DOI |
1 |
Rizzuti B., Sportelli L., Guzzi R. Evidence of reduced flexibility in disulfide bridge-depleted azurin: a molecular dynamics simulation study Biophysical Chemistry, 94: 107-120, 2001 | DOI |